ppat.1008487.s009.docx (14.4 kB)
Rhesus macaque tetherin genotypes.
journal contribution
posted on 2020-04-29, 17:52 authored by Aidin Tavakoli-Tameh, Sanath Kumar Janaka, Katie Zarbock, Shelby O’Connor, Kristin Crosno, Saverio Capuano 3rd, Hajime Uno, Jeffrey D. Lifson, David T. EvansThe tetherin alelles identified in each of the rhesus macaques included in this study (middle) are listed next to their corresponding animal identification numbers (left) and the virus (SIVmac239 or SIVmac239AAA) each animal was infected with (right). The allele designations (rBST-2.x) correspond to previously reported alleles of rhesus macaque tetherin [42].
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MHC I-downmodulationSERINC 5.nonhuman primate hostsanti-SERINC 5 activitySIV Neftetherin antagonismSIV mac 239 genomeimmunodeficiency viruses use NefRNANef impairs virus replicationwild-type SIV mac 239. Sequence analysisweek 24 post-infectionSIV mac 239 AAANef impairs SIV replicationdownmodulates cell-surface CD 4wild-type SIV mac 239rhesus macaques
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