ppat.1010020.s009.docx (20.69 kB)
Minimal Inhibitory Concentration (MIC) of isoniazid, Ethambutol, Rifampicin and Vancomycin for the parental M. tuberculosis H37Rv (WT) or the Δrv0180c::km mutant.
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posted on 2021-11-01, 17:35 authored by Delphine Payros, Henar Alonso, Wladimir Malaga, Arnaud Volle, Serge Mazères, Sébastien Déjean, Sophie Valière, Flavie Moreau, Stéphanie Balor, Alexandre Stella, Lucie Combes-Soia, Odile Burlet-Schiltz, Olivier Bouchez, Jérôme Nigou, Catherine Astarie-Dequeker, Christophe Guilhot(DOCX)
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toxic molecule attacksmall droplets containingmain causative agentknown carbohydrate ligandsinvade host cellsidentify genes importantearly events leadingphthiocerol dimycocerosate ),type parental strainmajor phagocytic receptormannan ), cr3rv0180c enhances entrymycobacterium tuberculosis cr3 ),receptor 3major adaptationtuberculosis rv0180c contributesrv0180c human tuberculosisvia used tnsequnknown functionsubstantially reducedsilencing cr3rv1779c rv1592c previously describednew perspectivemodulating lipidsmembrane receptorskm human populationfavor survivalcomplemented strainscell shapebacterial seeding
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