Public Library of Science
Browse
ppat.1008014.g001.tif (363.59 kB)

Mal and Cav1 gene expression is enriched in brain endothelial cells.

Download (363.59 kB)
figure
posted on 2019-11-08, 18:34 authored by Jennifer R. Linden, Claudia Flores, Eric F. Schmidt, Francisco A. Uzal, Adam O. Michel, Marissa Valenzuela, Sebastian Dobrow, Timothy Vartanian

(A) Heatmap showing the enrichment of cell type marker genes in the TRAP IPs from oligodendrocytes, endothelial cells, pericytes, astrocytes, L5b pyramidal cells, and inhibitory interneurons compared to whole cortex input. Gray boxes indicate a failure to detect (ND) the gene in the data set. (B, C) Mean ± SEM of the ratio of Mal (B) and Cav1 (C) expression (log2 fold change of RPKMs) in TRAP IP mRNAs compared to whole cortex input mRNAs in each of the CNS cell types from A. Dotted lines indicate 2-fold enrichment (positive value) or depletion (negative value).

History