VSG recognition by Nbs.
figure
posted on 2013-02-20, 17:35 authored by Benoît Stijlemans, Guy Caljon, Senthil Kumar A. Natesan, Dirk Saerens, Katja Conrath, David Pérez-Morga, Jeremy N. Skepper, Alexandros Nikolaou, Lea Brys, Etienne Pays, Stefan Magez, Mark C. Field, Patrick De Baetselier, Serge MuyldermansA) Rate plane with Isoaffinity Diagonals (RaPID) plot of Nb_An05 and the Nb_An05 mutants, Nb_An46 and Nb_An33 to VSG. The kinetic rate values kon and koff for a particular Nb to VSG determined via surface plasmon resonance are plotted on a two-dimensional graph so that pairings with identical KD values are located along isoaffinity diagonals.
