Fig_5.tif (250.91 kB)
Protection of scale drop syndrome by vaccination of Lates calcarifer.
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posted on 2015-08-07, 04:42 authored by Ad de Groof, Lars Guelen, Martin Deijs, Yorick van der Wal, Masato Miyata, Kah Sing Ng, Lotte van Grinsven, Bartjan Simmelink, Yvonne Biermann, Luc Grisez, Jan van Lent, Anthony de Ronde, Siow Foong Chang, Carla Schrier, Lia van der HoekKaplan-Meier survival curve of fish vaccinated with formalin-inactivated virus (FK-SDDV), binary ethyleneimine-inactivated virus (BEI-SDDV), recombinant MCP protein (recMCP), or diluent control vaccine (placebo). Twenty-eight days after vaccination the fish were challenged with 2 x 107 TCID50 SDDV per fish (intraperitoneal), mortality was scored until day 28 after challenge. All three vaccines provided >70% RPS against disease (p<0.001, Tarone-Ware test).