Multiple Alignments of CRs

Multiple alignments of the four CRs for a representative set of protein sequences (>15% dissimilarity over all four CRs) are shown. Sequences are identified by a species code (see Table 1), protein name (from literature as proposed in this paper), and database accession number, where available. The lengths of the sequences omitted between or within CRs are indicated in square brackets. The last row shows the secondary structure prediction obtained by jnetpred [65] for the human Stealth protein, where H stands for helices and E for beta-sheets. The color scheme used is the ClustalX default scheme, with the colors for conserved amino acids being more intense than those for nonconserved ones.