PLOS Computational Biology
Comparative study of population genomic approaches for mapping colony-level traits
The number of colonies which can be included is a GWAS for a given budget, in the alternative approaches.
Correlations between allele frequencies in individual genotypes and pool-seq.
Sequencing reads per colony before and after initial processing and after alignment based filtering.
A distribution of costs for a given budget when using different DNA extraction, library construction and sequencing methods.
Power of QTL identification for different levels of polyandry (or monoandry).
Power of QTL identification.
Allele dropout in pool-seq.
Allele frequency plots of whole genome sequencing (A) and RAD-seq (B) of pooled samples vs. individual samples from colony 50.