Exceptional structural examples of the center of rotation.

Region around the Center of Rotation (CoR), the Vα domain is shown in blue and the Vβ domain in red. Hydrogen atoms were added for the end-groups of the interacting amino acids. The average center of rotation is drawn as an orange sphere and the interacting residues are shown in licorice representation. CoR stabilizing interactions are drawn as a green line. For these six structures the highly conserved Q-Q interaction between the α and the β chains is replaced by the following residues (shown in licorice style): (A, D-F) αK (PDB-IDs: 1bd2, 3qiu, 3qiw, 3qjh), (B) βR (PDB-ID: 2esv), (C) αW (PDB-ID: 3gsn).