(CASE1) VEGF level pattern following initial capillary occlusion.

(A) VEGF level map shows localized synthesis of VEGF by Mueller cells in response to hypoxia in week 0. (B)—(D) Increasing number of Mueller cells actively produced VEGF in weeks 72, 124, and 152, where the pattern of regions with high VEGF reproduced that of the area with low oxygen tension. Color reflects magnitude of VEGF level. The redder the color the higher the VEGF level is. VEGF level has arbitrary unit (A.U.). “FAZ” in the figure refers to foveal avascular zone, “A” in red refers to arteriole, and “V” refers to venule.