ppat.1011417.g004.tif (1.46 MB)
The combined absence of both eIF4E1 and eIFiso4G1 enhances TuMV disease symptoms but impairs TuMV accumulation.
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posted on 2023-11-20, 18:46 authored by Delyan Zafirov, Nathalie Giovinazzo, Cécile Lecampion, Ben Field, Julia Novion Ducassou, Yohann Couté, Karen S. Browning, Christophe Robaglia, Jean-Luc Gallois(a) Phenotypic comparison of TuMV-inoculated representative plants of each genotype 14 dpi. (b) Rosette fresh weight analysis of TuMV-inoculated plants 14 dpi. n = at least 22 biological replicates. (c) Accumulation analysis of TuMV by DAS-ELISA 14 dpi. n = 16 biological replicates. Different letters depict significantly different groups identified by Kruskal–Wallis statistical tests at P < 0.05.
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viruses affecting plantsdiv >< palso promoting susceptibilitysupporting plant fitnessmany plant speciesfavoured virus multiplication>, whose inactivationrecent findings indicaterestricts virus accumulationplant translational apparatustruncated eifiso4g1 proteinrestrict tumv accumulationfunctional resistance proteinsnatural resistance allelesarabidopsis eif4e1 tumv accumulationplant healthtranslational machinerystill functionalnatural variabilitygenetic inactivationalleles mayfindings suggestfindings showeif4e1 eif4e tumv resultstumv ).potyvirus resistanceconferring resistancevirus hijackingtranslation initiationsuccessful subversionpreviously reportedlargest grouphost translationeif4e1 counteractsadverse effects
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