Influence of DNA-binding proteins and histone marks on enhancer-promoter contacts in human GM12878 cells.

a) Enhancer-promoter contacts depending on gene expression, as measured by interaction variable betas estimated using model (3). b) Long-range contacts of transcriptional factors with promoters depending on gene expression. c) Long-range contacts of histone modifications with promoters depending on gene expression. d) Long-range contacts of transcriptional factors with promoters depending on PolII pausing or elongation.