Illustration of a 2D version of the computational domain for two cells.

The domain consists of an extracellular domain Ω_e and two intracellular domains and with cell membranes Γ₁ and Γ₂. The intracellular domains are connected by the intercalated disc denoted by Γ_1,2, and the outer boundary of the extracellular domain is denoted by ∂Ω_e.