ppat.1007515.g002.tif (271.75 kB)
Diversity of vOTU specific activity.
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posted on 2019-01-10, 19:09 authored by John V. Dzimianski, Brianna S. Beldon, Courtney M. Daczkowski, Octavia Y. Goodwin, Florine E. M. Scholte, Éric Bergeron, Scott D. PeganActivity of vOTUs towards towards Ub-AMC (A) and human ISG15-AMC (B). Values shown are the mean ± standard deviation of two independent experiments.
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novel X-ray crystal structuresCrimean-Congo hemorrhagic fever virusRecent genomic characterizationISG 15 fluorogenic substratesHughes orthonairovirus speciesNairoviridae familyvOTU substrate preferencesDUBdeubiquitinase activity Post-translational modificationgene product 15nairovirus genomic diversitytumor domain protease
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