Correlation between replicates of the larval tick survival Tn-seq experiment.
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posted on 2019-05-14, 17:28 authored by James P. Phelan, Aurelie Kern, Meghan E. Ramsey, Maureen E. Lundt, Bijaya Sharma, Tao Lin, Lihui Gao, Steven J. Norris, Jenny A. Hyde, Jon T. Skare, Linden T. Hu(A) Correlation between the mutant compositions of the two replicate cultures of the input Tn library. (B) Correlation between the mutant compositions of the two replicate cultures of the Tn mutants recovered from the fed larvae (output library). Each data point represents the frequency of an individual Tn mutant in relation to the total input or output respectively. Each axis represents a different biological replicate.
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transposon insertion sequencingvivo screeningGenome-wide screen56 genesTn mutantsencode proteinsIxodes ticksburgdorferi survivalhost pathogen interactionnovel genesbiphasic life cyclecompetition assaysLyme diseaseBorrelia burgdorferi survivalBB 0017oxidative stressenzootic cyclebb 001746 genesborrelial virulence determinantsvector Borrelia burgdorferi
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