Amino acid composition of protrusions in IBS and nonIBS subsets, for domains containing at least one hydrophobic protrusion at their IBS.

Secondary structure elements of hydrophobic protrusions (A) and amino acid composition for all types of protrusions (B) at the IBS (blue) and on the rest of the domain (nonIBS, pink) with respective odds ratio values. Grey bars for log(OR) indicate a P-value under 0.05 and, therefore, non-statistical differences between the IBS and nonIBS datasets. The analyses are restricted to the proteins with at least one hydrophobic protrusion at the IBS.