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Data summary.
dataset
posted on 2023-09-18, 17:31 authored by Bayarbaatar Amgalan, Chi-Ping Day, Teresa M. PrzytyckaDE genes (tumor genes): differentially expressed genes selected based on T-test q-value < 0.01; Non-DE Genes: genes whose expressions are not differentiated between control and tumor samples; DE PCs: principal components which are differentiated between control and tumor samples representing potential impacts of Non-DE Genes (T-test q-value) on the transition mapping; TranNet: Pairs of Nodes in the Transition Network (DE Genes + DE PCs); Patients: Patients control and tumor samples are available (Clinical cohorts of the patients are summarized in Table B in S1 File); HN Genes: genes in both DE Genes and HumanNet-FN; HN Edges: Edges within HN Genes in the functional network.
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results allow usseveral cancer typescancer genome atlaspotential stromal facilitatorsfirst computational methodutilizes gene expressiongene expression profilesrelated immune responseadjacent control samplesmatched control samplesmany predictors identifiedgene expressionmatched controlcontrol samplescancer studiespredictors identifiedpotential regulatorspathways relatedimmune processescomputational approachtumor samplesxlink ">valuable resourceunderstanding rolestissue remodellingtcga ).prognostic biomarkersnormal crossinferred predictorsidentify predictorshealthy tissuesgrowing awarenessgenes associated
