ppat.1008177.g005.tif (192.21 kB)
De novo HIV adaptations occur in the child following transmission.
figure
posted on 2019-12-10, 18:39 authored by Jennifer Currenti, Abha Chopra, Mina John, Shay Leary, Elizabeth McKinnon, Eric Alves, Mark Pilkinton, Rita Smith, Louise Barnett, Wyatt J. McDonnell, Michaela Lucas, Francine Noel, Simon Mallal, Joseph A. Conrad, Spyros A. Kalams, Silvana Gaudieri(A) Significantly higher proportion of de novo adaptations were relevant to the paternal HLA allele than both maternal HLA alleles. (B) Gag and Nef had significantly more de novo adaptations relative to Pol. (C) There was no significant difference between de novo adaptations relevant to the different HLA loci. All analyses were performed as in Fig 4. N = 23, p<0.01 (**), p<0.05 (*). Data are represented as mean ± SE.
