Summary of phenotypes observed for NS5A mutants and PI4KIIIα silencing.
Silencing of shPI4KIIIα is given in italics.
PFIS mutants are given in bold italics.
1according to data obtained from figure 3B; +++: wt type or higher; ++: 10–99% wt; +: 1–9% wt; +/−: residual low level replication; −: no replication.
2according to data obtained from figure 2C; +++:wt or higher; ++: 50–99%wt; +: 26–49% wt; +/−: 20–25% wt; −: below 20% wt.
3according to data obtained from figure 4B; +++:>50%; ++: 26–50%; +: 11–25%; +/−: >5–10%; −: <5% of cells with MW clusters visible in IF.
4according to data obtained from figure 4C; +++:>4fold mock; ++: 3–4 fold mock; +: 2–3 fold mock; +/−: >1.5–2fold mock; −: 1–1.5fold mock.
5according to data obtained from figure 6B; +++: 1 or higher; ++: 0.5–0.9; +: 0.1–0.4.
§Data not shown.
*According to Reiss et al., CHM 2011.