Summary of phenotypes observed for NS5A mutants and PI4KIIIα silencing.

Silencing of shPI4KIIIα is given in italics.

PFIS mutants are given in bold italics.

1

according to data obtained from figure 3B; +++: wt type or higher; ++: 10–99% wt; +: 1–9% wt; +/−: residual low level replication; −: no replication.

2

according to data obtained from figure 2C; +++:wt or higher; ++: 50–99%wt; +: 26–49% wt; +/−: 20–25% wt; −: below 20% wt.

3

according to data obtained from figure 4B; +++:>50%; ++: 26–50%; +: 11–25%; +/−: >5–10%; −: <5% of cells with MW clusters visible in IF.

4

according to data obtained from figure 4C; +++:>4fold mock; ++: 3–4 fold mock; +: 2–3 fold mock; +/−: >1.5–2fold mock; −: 1–1.5fold mock.

5

according to data obtained from figure 6B; +++: 1 or higher; ++: 0.5–0.9; +: 0.1–0.4.

§

Data not shown.

*

According to Reiss et al., CHM 2011.