vOTU preferences for different di-Ub linkages.

<p>(A) Activity towards K48, K63, and K11 linked di-Ub FRET-TAMRA substrates. Values shown are the mean ± standard deviation of two independent experiments. (B) Gel cleavage assay of unlabeled di-Ub, visualized by Commassie Blue staining. (C) Summary of currently investigated vOTU di-Ub activity (present study and [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1007515#ppat.1007515.ref032" target="_blank">32</a>]).</p>