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Simulation video of mixing of disconnected weakly attractive chromosome beads (ϵ = 0.3 kBT) in small confinement (ϕ = 0.4) over a short time period (t = 103τ).

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posted on 2023-05-25, 17:45 authored by Gaurav Bajpai, Samuel Safran

Simulation video of mixing of disconnected weakly attractive chromosome beads (ϵ = 0.3 kBT) in small confinement (ϕ = 0.4) over a short time period (t = 103τ).

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Mesoscale, long-time mixing of chromosomes and its connection to polymer dynamics
PLOS Computational BiologyPLOS Computational Biology

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monomer subdiffusion duegeneric polymer simulationcondensin ii proteinssmall confinement volumesuggesting partial mixingnucleus ), increaseseven slower reptationdiv >< pdistinct territories withinchromosome mixing indexvolume fractionterritories overlapchromosome mixingstrong attractionsscaling exponentmicrophase separationdrosophila distinct chromosomesdemonstrates controlanimal cells

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