pntd.0011654.s013.pdf (608.87 kB)
The full version of the Maximum Likelihood (ML) trees of Fig 3.
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posted on 2023-09-18, 17:31 authored by Yu-ting Ren, Hong-pan Tian, Jia-le Xu, Man-qing Liu, Kun Cai, Shu-liang Chen, Xue-bing Ni, Yi-rong Li, Wei Hou, Liang-jun ChenPhylogenetic analysis based on the complete ORF sequences of (A) L, (B) M, and (C) S segments of Hubei SFTSVs and all available reference sequences. The full version of the Maximum Likelihood (ML) trees based on the Kimura 2-parameter model were constructed and tested by bootstrap analysis with 1,000 replications. The scale bar indicates the number of nucleotide substitutions per site, and the phylogenetic branches were supported with greater than 70% bootstrap values.
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virus genome variationlimited sample sizel genome sequenceshigher mortality comparedcase fatality rates88 virus strains8 recombination strainsleast 6 genotypesextensive genetic diversityhubei province basedthrombocytopenia syndrome virusphylogenetic analysis revealed2018 &# 8211viral genetic diversityhubei sftsv strainsclinical disease characteristics2022 hubei provincethrombocytopenia syndromedisease characteristicssftsv diversitygenetic exchangeviral mutationsfour genotypesclinical diseasessystematic researchsignificantly elevatedsftsv prevalentsftsv ),severe feverserum amyloidrelatively frequentprofound changesinflammatory biomarkerincidence areaemerging tickdynamic shiftdominant genotypedepth monitoringdata summarizeconducted timelyborne bunyavirus
