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Supplemental methods, figures and tables.

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journal contribution
posted on 13.05.2022, 17:43 by Brandon M. Invergo

S1 Text contains the following: Supplemental Methods—Additional details describing data sources, computational methods, and mathematical derivations of specificity models; Fig A—Using relative entropy as a PFM or PSSM column weight provides greater discrimination of columns than using information content; Fig B—Differing theoretical and empirical score ranges in scoring matrix-based models hinders the selection of a universal score cut-off; Fig C—A Venn diagram showing total coverage of the human kinome supported by four kinase-substrate prediction or assignment methods; and Table A—Protein kinases targeted by the chemical inhibitors used in the quantitative phosphoproteomic experiment of Wilkes et al.[41].