Sulpiride does not affect glucagon levels in mice.
journal contribution
posted on 2024-04-18, 17:55 authored by Dina I. Vázquez-Carrillo, Ana Luisa Ocampo-Ruiz, Arelí Báez-Meza, Gabriela Ramírez- Hernández, Elva Adán-Castro, José Fernando García-Rodrigo, José Luis Dena-Beltrán, Ericka A. de los Ríos, Magdalena Karina Sánchez-Martínez, María Georgina Ortiz, Gonzalo Martínez de la Escalera, Carmen Clapp, Yazmín MacotelaGlucagon levels were measured in serum after 30 days of sulpiride treatment using a mouse ELISA kit after 4 h of fasting. White circle: vehicle treatment; black rhombus: sulpiride treatment.
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type 2 diabetesdopamine d2 receptorsincreased glycogen storesantipsychotic drug sulpiridehigh fat dietsulpiride reduces obesitysulpiride reducing hyperglycemiaprolactin receptor activityincreased prevalencesulpiride treatmentreduced hyperglycemiainsulin receptorinduced hyperglycemiareduces visceraltherapeutic potentialskeletal musclepancreatic levelsobese ratsobese micenormalized markerslow levelsinsulin resistanceimproves metabolismhormone prolactinfindings supportalso observedadipose tissueadipocyte hypertrophy30 days
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