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Charrasse, Sophie; Racine, Victor; Saint-Omer, Charlotte; Poquillon, Titouan; Lionnard, Loïc; Ledru, Marine; Gonindard, Christophe; Delaunois, Sandrine; Kissa, Karima; Frye, Richard E.; Pastore, Manuela; Reynes, Christelle; Frechet, Mathilde; Chajra, Hanane; Aouacheria, Abdel

doi:10.1371/journal.pone.0301372.s001

Raw results and plots.

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posted on 2024-03-28, 17:35 authored by Sophie Charrasse, Victor Racine, Charlotte Saint-Omer, Titouan Poquillon, Loïc Lionnard, Marine Ledru, Christophe Gonindard, Sandrine Delaunois, Karima Kissa, Richard E. Frye, Manuela Pastore, Christelle Reynes, Mathilde Frechet, Hanane Chajra, Abdel Aouacheria

The raw data are accessible at https://doi.org/10.48579/PRO/ROSLGY. XLS_raw_data: content of the datasets used for statistical analysis; BERG_plots: plots made with R for the experiments with the natural ingredient Bergaphen-15; CANCER_plots: plots made with R for the experiments using human normal versus cancer fibroblasts; NHDF_NHEK_plots: plots made with R for the experiments using normal human dermal fibroblasts and normal human epidermal keratinocytes; TOXICANTS_plots: plots made with R for the experiments using toxicant-treated cells; UVB_plots: plots made with R for the experiments using UVB-irradiated cells.

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throughput drug screening rich datasets gathered protective natural ingredient introduced two innovations innovative computerized method confocal fluorescence images called mitosigils ).including cancer tissue stressed dermal fibroblasts monitoring cell health living adherent cells mitochondrial network morphology tissue homeostasis network architecture normal fibroblasts derived fibroblasts cell types cell biology mitochondrial shape mitochondrial organization mitochondrial morphology xlink ">various structural various mito thirty features stress responses sensitively discriminate semiotic phenotyping semiotic analysis research areas quantitative results quantitative imaging quantify changes proprietary software pesticide exposure novel wet novel algorithm named mitotouch morphospace diagrams hydrogen peroxide human diseases functional states facilitate interpretation exhaustive analysis excellent organelles enables accurate effective analysis deleterious impact cellular contexts cellular configurations broader applications basal conditions accurately analyze

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