Definition of Shield subtypes.
journal contribution
posted on 2023-06-05, 17:29 authored by Elliot Macdonald, Rosanna Wright, James P. R. Connolly, Henrik Strahl, Michael Brockhurst, Stineke van Houte, Tim R. Blower, Tracy Palmer, Giuseppina MarianoFlaGs output representing the genomic neighbourhood of shdA genes belonging to different subtypes. The spectrum of genomes encoding these homologues is reported in S2–S5 Tables. FlaGs-grouped genes are numbered and coloured by FlaGs according to their association to a certain cluster. FlaGs-numbering of clustered genes is reported in S4 Table. Clustered genes were annotated as belonging to a specific antiphage system using PFAM and Defense-finder. These annotations are reported in S4 Table. shdA genes are coloured in blue and partner genes have a coloured outline as indicated on the figure.
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provide additional linesnew player withinfrequently encoded togetherdiv >< pcontain additional componentsbound protein harboringmediate bacterial immunityshda confer populationcore component shdabacterial immunity arsenalhost chromosomal dnashield system compriseslevel immunityphage systemheterologous hostdegrade dnadefensive arsenalshda homologuesshda alonevitro termed shieldseveral phagesrmuc domainsrmuc domainresults identifyrecent yearspseudomonas phage systemsphage defensenovel mechanismnegatively affectheterologous productionfour subtypesforms partcompetitive bacteriabioinformatic approachesbacteriophage interactions
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