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siRNA knock down of pp32 increased sensitivity to GEM.

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posted on 29.11.2010 by Timothy K. Williams, Christina L. Costantino, Nikolai A. Bildzukewicz, Nathan G. Richards, David W. Rittenhouse, Lisa Einstein, Joseph A. Cozzitorto, Judith C. Keen, Abhijit Dasgupta, Myriam Gorospe, Gregory E. Gonye, Charles J. Yeo, Agnieszka K. Witkiewicz, Jonathan R. Brody

(A) Immunoblot analysis of pp32 abundance in lysates from PL5 cells 48 h after transfection. In cells transfected as explained in (A), the sensitivity to GEM (B) or etoposide (C) was tested by PicoGreen cell survival assay.

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