Ex vivo PA imaging results.
CFZ-HCl NP signal normalized to the THb signal for prostates of (A) diluent injected TRAMP mice (DIL-TMP), (B) CFZ-HCl NP injected normal mice (CFZ-NOR), and (C) CFZ-HCl NP injected TRAMP mice (CFZ-TMP). Color bars indicates the CFZ-HCl NP signal normalized to the THb signal as determined by the two-wavelength unmixing. (D) Mean normalized CFZ-HCl NP signal for each group within the organ boundaries as delineated by the US image (shown in the representative images as a white dotted line). * p-value < 0.05, ** p-value < 0.01.