Figure_6.tif (517.7 kB)
dhfr triple mutant He changes over time (51I/108N/164L).
figure
posted on 2013-03-16, 10:00 authored by Sean M. Griffing, Giselle M. Rachid Viana, Tonya Mixson-Hayden, Sankar Sridaran, Mohammad Tauqeer Alam, Alexandre Macedo de Oliveira, John W. Barnwell, Ananias A. Escalante, Marinete Marins Povoa, Venkatachalam UdhayakumarThe figure shows variation in He surrounding dhfr for parasites carrying the 51I/108N/164L mutant during the 1980s (n = 8) and 1990s (n = 19). He surrounding this allele appears to have increased between the two periods. The two flat, dashed lines represent two different estimates of neutral He in Brazil.