Weight gain and Food intake of C57Bl6, alb-SREBP-1aΔP and alb-SREBP-1a transgenic animals.

Male C57Bl6, alb-SREBP-1aΔP and alb-SREBP-1a mice (n = 20 per genotype) were housed as groups of four under standard conditions with unlimited access to water and regular chow (13.0 MJ/kg: 53% carbohydrates, 11% fat, 36% protein). Weight gain (A) and Food intake (B) were measured once a week starting at weaning and monitored for an observation period of 18 weeks. Body weight (C), liver weight ((D) and WAT weight (E) were determined at sacrification. WAT contend per body weight (F), food uptake per body weight and (G) weight gain per food uptake (H) were determined in each group of mice. Data are given as means including standard deviation (±SD).