WIP1 expression correlates with neuroblastoma disease stage.

A, Analysis of a large patient cohort (88 patients) with annotated clinical data and long term follow up (Versteeg-88-Mas5.0) demonstrates higher PPM1D levels in stage 4 metastatic subgroup (# = p < 0.01, # # = p < 0.005, by Student T-test). B, Long-term survival was also significantly (Kaplan-Meier analysis p = 0.005) different for high (n = 50) versus low (n = 38) expression of PPM1D.