Viable viral load (pfu/ml) for each experimental animal found in scarification site (A) and secondary lesion swabs (B) throughout the study.
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posted on 2015-10-30, 02:44 authored by Christina L. Hutson, Yoshinori J. Nakazawa, Joshua Self, Victoria A. Olson, Russell L. Regnery, Zachary Braden, Sonja Weiss, Jean Malekani, Eddie Jackson, Mallory Tate, Kevin L. Karem, Tonie E. Rocke, Jorge E. Osorio, Inger K. Damon, Darin S. Carroll(A) The maximum viral load from the scarification site was 1.05X108 in an animal challenged with West African MPXV and 1.64X107 for an animal challenged with Congo Basin MPXV. No viable virus was found in sample days after day 27 post infection (p.i.) (B) Lower loads of viable virus were recovered from secondary lesion swabs during a shorter period of time (day 3 p.i. to 21 p.i.); the maximum viral load was 3.88X104 for an animal infected with Congo Basin MPXV and 6.27X103 for an animal infected with West Africa MPXV.
