Fig_5.tif (1.17 MB)
Validation of the hit compounds using Brugia pahangi adult female worms.
figure
posted on 2016-01-28, 12:42 authored by Elizabeth Bilsland, Daniel M. Bean, Eileen Devaney, Stephen G. OliverChemical structures were obtained from www.chemspider.com. The IC50 for each of the compounds in human fibroblasts (MRC5) is shown in the last column [26]. The IC50 of Geldanamycin against different human cell lines is a consensus of multiple data available in the literature (www.medchemexpress.com/Geldanamycin.html).
