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Up-regulation of nidogen 1 mRNA and protein in PDGFC Tg and Pten null tumors.

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posted on 2011-06-23, 01:01 authored by Keane K. Y. Lai, Sufen Shang, Neha Lohia, Garrett C. Booth, Derek J. Masse, Nelson Fausto, Jean S. Campbell, Laura Beretta

A,C) Expression of nidogen 1 mRNA and protein was measured by quantitative PCR and Western-blot, in PDGFC Tg fibrotic liver, in PDGFC Tg tumor and adjacent tissue and in age-matched WT liver. B,D) Similarly, expression of nidogen 1 mRNA and protein was measured in Pten null steatotic liver, in Pten null tumor and adjacent tissue, and in age-matched control liver. Expression in the disease groups is represented as fold changes over the mean of expression in the control groups.

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