Figure_3.tif (780.19 kB)

Twitch-contraction (0.1 ms, 2 Hz, 2 min) signaling in AMPK transgenic soleus muscles.

Download (0 kB)
figure
posted on 21.02.2013, 10:30 by Thomas E. Jensen, Peter Schjerling, Benoit Viollet, Jørgen F. P. Wojtaszewski, Erik A. Richter

A) α1 AMPK and B) α2 AMPK activities in wildtype vs. kinase-dead (KD) AMPK muscles (n = 7–8), C ) α1 AMPK and D) α2 AMPK activities in wildtype vs. α1 AMPK KO muscles (n = 7–10), E ) α1 AMPK and F) α2 AMPK activities E) and F) wildtype vs. α2 AMPK (n = 10). G) Basal and twitch-stimulated AS160 phosphorylation in wildtype vs. AMPK transgenic muscles (n = 6–9). As a positive control, insulin-stimulated (2000 µU/ml, 15 min) soleus was included (n = 1). * p<0.05 vs. basal. ††/††† p<0.01/0.001 genotype main effect.

History

Usage metrics

PLOS ONE

Licence

Exports