posted on 2014-12-23, 02:42authored byD. Kienhöfer, J. Hahn, I. Schubert, C. Reinwald, N. Ipseiz, S. C. Lang, È. Bosch Borràs, K. Amann, C. Sjöwall, A. E. Barron, A. J. Hueber, B. Agerberth, G. Schett, M. H. Hoffmann
(A) Classification of lung pathology in pristane-injected mice. Representative images and H&E-stainings of C57BL/6 mice two weeks after pristane-injection, with lungs showing no hemorrhage, partial, or full hemorrhage. Scale bars, 200 µm. (B) Time course of pristane-induced alveolar hemorrhage in WT and CRAMP−/− mice. Incidence and types of gross pathology at day 0, day 14, and day 180 after pristane-injection. (C) Low mortality after pristane-injection in both CRAMP+/+ (n = 14) and CRAMP−/− (n = 15) mice. No significant differences could be found by Logrank test.