The overall structure of S. pneumoniae GHIP.

(A) The structure of S. pneumoniae GHIP in stereo view. (B) The topological diagram of S. pneumoniae GHIP. The barrels and arrows indicate the helix and β-strand structures. (C) The electrostatic potential surface of S. pneumoniae GHIP. Saturated red indicates Φ<−10 kiloteslas/e, and saturated blue indicates Φ>10 kiloteslas/e, T = 20°C. The magenta arrow points towards the negatively charged groove.