The nucleosome acidic patch and histone ubiquitination.
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posted on 2014-03-06, 03:00 authored by Justin W. Leung, Poonam Agarwal, Marella D. Canny, Fade Gong, Aaron D. Robison, Ilya J. Finkelstein, Daniel Durocher, Kyle M. MillerSummary of our results within the context of the nucleosome structure. The acidic patch is required for RNF168- and RING1B/BMI1-dependent histone ubiquitination and LANA inhibits these processes. See text for details. Nucleosome structure was created in Pymol as previously described [20].
