Fig_3.tif (5.52 MB)
The localization of miR-21 in invasive cervical cancer tissues.
figure
posted on 2015-05-26, 15:16 authored by Sureewan Bumrungthai, Tipaya Ekalaksananan, Mark Francis Evans, Peechanika Chopjitt, Thumwadee Tangsiriwatthana, Natcha Patarapadungkit, Pilaiwan Kleebkaow, Sanguanchoke Luanratanakorn, Bunkerd Kongyingyoes, Suchin Worawichawong, Chamsai PientongA and B: tissue sections from cervical cancer samples were incubated with DIG-labeled locked nuclei acid (LNA) probe to miR-21. Strong signals were observed in the stroma. The signal was also seen at the rim of cancer cells adjacent to the stroma (Bar: 100 μm). C: RNU6B staining in cervical cancer and stromal nuclei (Bar: 50 μm). D: cervical cancer negative control staining using a ‘scramble’ LNA probe (Bar: 50 μm).