Figure_1.tif (274.67 kB)
The increase in apparent odds ratio after selecting samples with in the top or bottom %.
figure
posted on 2013-10-18, 03:01 authored by Luke Jostins, Adam P. Levine, Jeffrey C. BarrettColoured lines represent different amounts of variance explained by the risk score . The odds ratios in unselected individuals were 1.2, 2 and 4, the disease was assumed to have prevalence , and the allele frequency was assumed to be .