Figure_5.tif (186.34 kB)
The increase in ASM activity observed in diabetic EPCs is prevented by DHA-rich fish oil diet.
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posted on 2013-02-19, 16:27 authored by Maria Tikhonenko, Todd A. Lydic, Madalina Opreanu, Sergio Li Calzi, Svetlana Bozack, Kelly M. McSorley, Andrew L. Sochacki, Matthew S. Faber, Sugata Hazra, Shane Duclos, Dennis Guberski, Gavin E. Reid, Maria B. Grant, Julia V. BusikDiabetic bone marrow EPC showed a significant increase in ASM activity. However, the EPCs derived from diabetic animals fed DHA-rich fish oil diet showed reduced ASM activity that was similar to that observed in control rats. n = 8 controls, n = 3 in diabetes soybean oil diet, n = 5 in diabetes fish oil diet. *** = p<0.001 compared to control animals group and ### = p<0.001 compared to diabetic animals fed with soybean oil diet.
