The increase in ASM activity observed in diabetic EPCs is prevented by DHA-rich fish oil diet.

Diabetic bone marrow EPC showed a significant increase in ASM activity. However, the EPCs derived from diabetic animals fed DHA-rich fish oil diet showed reduced ASM activity that was similar to that observed in control rats. n = 8 controls, n = 3 in diabetes soybean oil diet, n = 5 in diabetes fish oil diet. *** = p<0.001 compared to control animals group and ### = p<0.001 compared to diabetic animals fed with soybean oil diet.