The expression of Schwann cell markers in murine sciatic nerve.

Immunofluorescence staining of sciatic nerve vertical section from newborn (A-J) and adult (a-j) mice. (A, a) S100; (B, b) Sox10; (C, c)Oct6 failed to be detected in adult SN whereas newborn SN is Oct6 positive; (D, d) Krox20; (E, e)Sox2 was not expressed in both newborn and adult SN; (F, f) P75^NTR; (G, g)NCAM; (H, h)GAP43; (I, i) MBP; (J, j) MPZ. (K) Real-time quantitative RT-PCR analysis of mRNA expression in newborn and adult mice SN. S100 mRNA level in adult SN increased while that of Sox10, Oct6, P75^NTR, NCAM, GAP43 decreased during culture in vitro. *P<0.05. Scale bar = 100μm.