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The Rhox cluster is classified into two regulated regions by DNA methylation.

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posted on 07.10.2011, 02:01 by Takayuki Isagawa, Genta Nagae, Nobuaki Shiraki, Takanori Fujita, Noriko Sato, Shumpei Ishikawa, Shoen Kume, Hiroyuki Aburatani

a) Overview of the DNA methylation profile of the Rhox cluster. b) The DNA methylation status of anterior and posterior Rhox genes. The left panel represents the MeDIP signal in each Rhox promoter. The right panel shows the quantitative estimation of DNA methylation by MALDI/TOFMAS. The arrowhead indicates the region of DNA analyzed for methylation. c) Expression profile of anterior and posterior Rhox genes.

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