Terminase phylogeny.

Maximum-likelihood tree of known representative terminase genes along with all identified terminases in the uncultured MedDCM viral contigs (uvMED) and putative prophage terminases (401 uvMED, 631 in total). Branches in the tree are colored according to the following codes: black, sequences from cultured phages; blue, putative prophage derived sequences; red, uncultured phage terminases obtained in this study. Known terminase types are labeled in bold. The microbes from which the putative prophage terminases were identified are marked by colored circles in the tree and a key is provided below. Bootstrap support of nodes is indicated on selected nodes. The terminase of pelagiphage HTVC010P is also labeled.