TRAMP^fmsmic-1 mice survive longer and have smaller prostate tumors than TRAMP mice.

Overall survival of individual mice from birth to death is shown (panel A). The survival data for TRAMP (—▴—) and TRAMP^fmsmic-1 (—Δ—) mice were plotted using the Kaplan-Meier method. The log-rank statistic for median survival time is shown. The genitourinary (GU), seminal vesicle (SV) and prostate tumor sizes in TRAMP^fmsmic-1 and TRAMP mice (n = 15/group) sacrificed at 8, 17, 25 and 33 weeks of age are shown in panel B, C and D. The GU (panel B), SV (panel C) and prostate weights (panel D) are presented as mean mg weight/g body weight ± SEM. p values are shown as *p<0.05; **p<0.01; ***p<0.001.