Figure_4.tif (1.61 MB)
Structural model Plasmodium falciparum lactate dehydrogenase (pfLDH) (PDB: 1CEQ) with NADH binding site (yellow color)
figure
posted on 2013-09-24, 02:24 authored by Komal Kalani, Jyoti Agarwal, Sarfaraz Alam, Feroz Khan, Anirban Pal, Santosh Kumar Srivastava(A). Superimposition of the best conformation of GA (in purple), CQ (in yellow) and NADH (in orange) in the active site pocket of P. falciparum enzyme lactate dehydrogenase pfLDH) (B). 2-D diagrams illustrating protein-ligand interactions: (C) Compound CQ; (D) Compound GA.