Single-cell rendering of tumor cells.

The green cells are normal tumor cells and the yellow cells are hypoxic cells. The preexisting vasculature is rendered in red. A) Day 10: a spherical tumor without angiogenesis withnormal tumor cells only present near blood vessels. B) Day 60: A cylindrical tumor with angiogenesis, diameter 300 µm and length 800 µm. The purple cells are active neovascular cells which are not rendered individually. The white arrow indicates a vascular cell incorporated into a neovascular branch. Axes are labeled in µm.