Schematic diagram showing α-TEA to induce breast cancer cells to undergo apoptosis via caspase-8 mediated ER stress JNK/CHOP/DR5 amplification loop and by down-regulation of anti-apoptotic mediators c-FLIP (L) and Bcl-2.
posted on 2013-02-21, 00:26authored byRicha Tiwary, Weiping Yu, Jing Li, Sook-Kyung Park, Bob G. Sanders, Kimberly Kline
Schematic diagram showing α-TEA to induce breast cancer cells to undergo apoptosis via caspase-8 mediated ER stress JNK/CHOP/DR5 amplification loop and by down-regulation of anti-apoptotic mediators c-FLIP (L) and Bcl-2.