Reduced Synaptic Inhibition Perturbs Spinalized Fictive Motor Output Without Disrupting Episodic Structure.

(A–B) Representative traces of the fictive motor output from a representative spinalized larva in 50 µM NMDA (A) and following application of 1 µM Strychnine (B). Top traces are episodes of fictive motor activity; bottom traces show bursts in the indicated regions at a finer time scale. (C–F) Plots of episode frequency (C), episode duration (D), burst frequency (E) and burst duration (F) in Baseline (50 µM NMDA), Strychnine (50 µM NMDA, 1 µM Strychnine), and Washout (50 µM NMDA) conditions. * Statistically significant difference.