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Reconstruction of ovarian cancer progression.

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posted on 2014-10-09, 03:45 authored by Loes Olde Loohuis, Giulio Caravagna, Alex Graudenzi, Daniele Ramazzotti, Giancarlo Mauri, Marco Antoniotti, Bud Mishra

Trees reconstructed by oncotrees and CAPRESE (with , with the same tree is reconstructed). The set of CGH events considered are gains on , and and losses on , , and . Events on chromosomes arms containing the key genes for ovarian cancer are in bolded circles. In the left tree all edge weights are the observed probabilities of events. In the right the full edges are the causation inferred with the PR and the weights represent the scores used by CAPRESE. Weights on dashed lines are as in the left tree.

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