RIC reduces heart infarct size in the acute, delayed and chronic phases of conditioning.

(A) Infarct size expressed as percentage of left ventricle area for each of the treatment groups. Values are means ± S.E.M. An (*) denotes a statistically significant difference compared to controls (P<0.05). (B) Representative cross-sections of mouse hearts from each of the treatment groups after I/R and staining with TTC to visualize the infarcted area.